Gerald Kerkut Trust Symposium
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| Coffee | 08:45 - 09:15 |
| Welcome and introduction from Prof. Robert Walker | 09:15 - 09:30 | Stephanie Turner (i) (Arjuna Ratnayaka, Andrew Lotery, David Tumbarello)Induction of lysosomal biogenesis in the retinal pigment epithelium (RPE) as a novel treatment for Stargardt disease |
09:30 - 09:45 |
James Lamb (i) (James Dillon, Katrin Deinhardt, Vincent O’Connor)Characterising a subset of ASD risk genes using C.elegans, with example jmjd-3.1 |
09:45 - 10:00 |
Daisy Bown (i) (Matthew Terry, Lorraine Williams)The role of TaPIF3 in regulating growth of hexaploidy wheat |
10:00 - 10:15 |
Ayesha Mohuid Din (i) (Herman Wijnen, Marc Dumont)Mechanisms underlying environmental control of oviposition in Drosophila |
10:15 - 10:30 |
| Coffee | 10:30 - 11:15 |
| Chair Dr Niall Horn | |
Suzanne Buss (i) (Diego Gomez-Nicola, Mariana Vargos Caballero)Unveiling and mapping the complexity of the immune compartment in human Alzheimer’s disease |
11:15 - 11:30 |
Shane Johnson (i) (Karen Lillycrop, Keith Godfrey, Emma Garratt)Identifying the cause of muscle stem cell aging and novel therapeutic strategies |
11:30 - 11:45 |
Sonakshi Gehlot (i)(Marcin Przewloka, Nullin Divecha)Is nuclear speckle localized PIP2: a critical signalling nexus between DNA damage and central control of splicing and transcription |
11:45 - 12:00 |
Jiaoqi Cheng (i) (Salah Elias, Stephen Beers) Multiplex in situ imaging and deep learning to investigate the contribution of abnormal cell divisions to breast tumour heterogeneity |
12:00 - 12:15 |
Joshua Green Jenkinson (i)(Nicole Prior, Jonathan Swann)Investigating the regulatory role of central carbon metabolism on cell fate decisions during liver development and regeneration |
12:15 - 12:30 |
| Lunch | 12:30 - 14:00 |
| Chair Dr Alan Thomas | |
Ellie Seaby (iii) (Sarah Ellis, Heidi Rehm)The integration of clinical samples with 300,000 reference exomes and genomes for health and disease |
14:00 - 14:15 |
Amber Cooper (ii) (Amrit Mudher, Herman Wijnen, Katrin Deinhardt)Tau gene structure-function relationships: How do Genetic Variations in the Tau Gene MAPT Influence Tau-Mediated Degeneration |
14:15 - 14:30 | Christina Georgiadou (ii)(Jessica Teeling, Phil Williamson) The interaction between FcyRIIB and αSN conformers and the implications in Parkinson’s disease |
14:30 - 14:45 |
| Tea | 15:45 - 15:30 |
| Chair Dr Alan Thomas | |
Brad Richardson (iii) (Amrit Mudher, Herman Wijnen)How do neurons age and do these changes confer an increased vulnerability to disease? |
15:30 - 15:45 |
Lucy Scullard (iii) (Vincent O’Connor, Katrin Deinhardt)The Cysteine String Protein a PARADIGM: synaptic proteostasis for neuronal stability in health and disease |
15:45 - 16:00 |
Naomi Thorne (iii)(David Tumbarello, Roxana Carare)Investigating the relationship between alpha-synuclein and mitochondrial quality control mechanisms |
16:00 - 16:15 |
| Short General Discussion about Trust activities | 16:30 |