Gerald Kerkut Trust Symposium
10th July 2023
King Edward VI School


This was a day-long symposium during which postgraduates funded by the trust gave talks on their work. More images.


Programme

Coffee 08:45 - 09:15
 Welcome and introduction from Prof. Robert Walker 09:15 - 09:30
 Stephanie Turner (i) (Arjuna Ratnayaka, Andrew Lotery, David Tumbarello)
  Induction of lysosomal biogenesis in the retinal pigment epithelium (RPE) as a novel treatment for Stargardt disease
09:30 - 09:45
 James Lamb (i) (James Dillon, Katrin Deinhardt, Vincent O’Connor)
 Characterising a subset of ASD risk genes using C.elegans, with example jmjd-3.1
09:45 - 10:00
 Daisy Bown (i) (Matthew Terry, Lorraine Williams)
 The role of TaPIF3 in regulating growth of hexaploidy wheat
10:00 - 10:15
 Ayesha Mohuid Din (i) (Herman Wijnen, Marc Dumont)
 Mechanisms underlying environmental control of oviposition in Drosophila
10:15 - 10:30
Coffee 10:30 - 11:15
Chair Dr Niall Horn
 Suzanne Buss (i) (Diego Gomez-Nicola, Mariana Vargos Caballero)
 Unveiling and mapping the complexity of the immune compartment in human Alzheimer’s disease
11:15 - 11:30
 Shane Johnson (i) (Karen Lillycrop, Keith Godfrey, Emma Garratt)
 Identifying the cause of muscle stem cell aging and novel therapeutic strategies
11:30 - 11:45
 Sonakshi Gehlot (i)(Marcin Przewloka, Nullin Divecha)
 Is nuclear speckle localized PIP2: a critical signalling nexus between DNA damage and central control of splicing and transcription
11:45 - 12:00
 Jiaoqi Cheng (i) (Salah Elias, Stephen Beers)
 Multiplex in situ imaging and deep learning to investigate the contribution of abnormal cell divisions to breast tumour heterogeneity
12:00 - 12:15
 Joshua Green Jenkinson (i)(Nicole Prior, Jonathan Swann)
 Investigating the regulatory role of central carbon metabolism on cell fate decisions during liver development and regeneration
12:15 - 12:30
Lunch 12:30 - 14:00
Chair Dr Alan Thomas
 Ellie Seaby (iii) (Sarah Ellis, Heidi Rehm)
 The integration of clinical samples with 300,000 reference exomes and genomes for health and disease
14:00 - 14:15
 Amber Cooper (ii) (Amrit Mudher, Herman Wijnen, Katrin Deinhardt)
 Tau gene structure-function relationships: How do Genetic Variations in the Tau Gene MAPT Influence Tau-Mediated Degeneration
14:15 - 14:30
 Christina Georgiadou (ii)(Jessica Teeling, Phil Williamson)
 The interaction between FcyRIIB and αSN conformers and the implications in Parkinson’s disease
14:30 - 14:45
Tea 15:45 - 15:30
Chair Dr Alan Thomas
 Brad Richardson (iii) (Amrit Mudher, Herman Wijnen)
 How do neurons age and do these changes confer an increased vulnerability to disease?
15:30 - 15:45
 Lucy Scullard (iii) (Vincent O’Connor, Katrin Deinhardt)
 The Cysteine String Protein a PARADIGM: synaptic proteostasis for neuronal stability in health and disease
15:45 - 16:00
 Naomi Thorne (iii)(David Tumbarello, Roxana Carare)
 Investigating the relationship between alpha-synuclein and mitochondrial quality control mechanisms
16:00 - 16:15
Short General Discussion about Trust activities 16:30

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