Gerald Kerkut Trust Symposium
Summer 2020

This was an online symposium during which postgraduates funded by the trust gave talks on their work.

Programme

Ellie Seaby (2) (Sarah Ennis, Heidi Rehm)  A bespoke gene to patient approach uplifts novel gene discovery for rare diseases.

Helena Rawsthorne (4) (Lindy Holden-Dye, James Dillon)  Investigating autism associated genes in C. elegans reveals candidates with a role in social behaviour

Dawn Cooper (3) (Matthew Loxham, Emily Swindle, Damon Teagle)  Investigating the effects of co-exposure to airborne house dust mite (HDM) and particulate matter (PM) on bronchial epithelial cells

Maria Fankhaenel (4) (Salah Elias, Keith Jones)  Identification of Annexin A1 as a novel regulator of mitotic spindle orientation in mammary epithelial cells

Jessica Bampton (4) (Matthew Terry, Haruko Okamoto)  The role of singlet oxygen signalling in chloroplast development

Gabriele Zalaite (2) (Jessica Teeling, Phil Williamson)  The role of FcγRIIb in Parkinson’s Disease

Rebecca Carter (3) (Lorraine Williams)  Investigating Zn homeostasis in the crop plant barley using CRISPR/Cas9 gene editing

Hannah Warming (3) (Mariana Vargas-Cabalerro, Ian Galea, Diederik Bulters)  Neurotoxicity of haemoglobin and the recovery of neuronal function in subarachnoid haemorrhage

Kathryn Hussey (2) (Hannah Siddle, Edd James, Emma Reeves)  Investigating the role of MHC class I molecules in immune evasion by tumour cells

Evelin Szalai (4) (Marcin Przewloka, Paul Skipp)  Mechanistic insight into the regulatory role of the key Drosophila kinetochore protein Spc105R

Monica Guerrero-Carrasco (4) (Diego Gomez-Nicola, Mariana Vargas-Cabalerro)  Understanding the role of inflammatory pre-conditioning on the onset of Alzheimer's Disease

Stephanie Robinson (4) (Peter Lackie, Tina Roose)  3D Imaging of Peripheral Pulmonary Lymphatics To Model Fluid Flow In Human Health And Disease

Ben Bachelor (3) (Amrit Mudher)  Investigating the spread of pathological Tau in Alzheimer's disease

Lloyd Steele-Nicholson (2) (Melissa Andrews, David Tumbarello)  Increasing axonal expression of α9β1 integrin to promote axon regeneration: exosome-mediated delivery and axon-targeting of the α9 integrin subunit

Lauren McNicholas (3) (Katrin Deinhardt, Mariana Vargas-Caballero)  Can Fyn inhibition rescue early synaptic dysfunction in Alzheimer's Disease?

Laura Cooke (2) (Jane Cleal, Jaswinder Sethi, Pam mahon, Nicholas Harvey)  Getting a handle on placental mechanisms of vitamin D handling

Dianne Lopez (3) (Katrin Deinhardt, Mark Coldwell, Jonathan West)  Investigating the mechanisms of tau propagation in neurodegenerative diseases

Steve John (3) (Matthias Baud, Rob Ewing, Graham Packham, Paul Skipp)  Small molecule modulation of the wnt pathway: Protein-protein interaction networks and therapeutic outlook

Jacob Trend (2) (Claire Clarkin, Katrin Deinhardt, Phillip Schneider)  Does a common aetiology between Alzheimer’s disease and osteoporosis exist?

Mike Price (2) (Herman Wijnen, Mariana Vargas-Caballero)  Light-Mediated Switching of Circadian Pacemaker Function Across the Neural Clock Circuit of Drosophila